Extracurricular laboratory: Synthetic route of 42514-50-1

According to the analysis of related databases, 42514-50-1, the application of this compound in the production field has become more and more popular.

Electric Literature of 42514-50-1, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 42514-50-1, name is 3-Amino-3-methylbutan-1-ol. This compound has unique chemical properties. The synthetic route is as follows.

48.7 mL (668 mmol) thionyl chloride were slowly added dropwise at 0 C. with vigorous stirring to a solution of 53.0 g (514 mmol) 3-amino-3-methyl-butanol in 255 mL methylene chloride/dimethylformamide (50:1). After the addition had ended the reaction mixture was refluxed for 1 h at reflux temperature and then stirred for 16 h at ambient temperature. The solvent was removed and the residue was combined with 50 mL acetonitrile with stirring. The solid was filtered off and dried for 18 h at 45 C. 67.9 g (430 mmol, 84%) 3-chloro-1,1-dimethylpropylamine-hydrochloride were obtained as a colourless solid.

According to the analysis of related databases, 42514-50-1, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Boehringer Ingelheim International GmbH; US2005/245526; (2005); A1;,
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Alcohols – Chemistry LibreTexts