Extracurricular laboratory: Synthetic route of Ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 94687-10-2, name is Ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate. This compound has unique chemical properties. The synthetic route is as follows. Computed Properties of C20H24O7

£’rytftro-l-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-l,3-propanediol (2g): (0178) (0179) 2g (0180) Scheme 8. Synthesis of i?? i zro-l-(3,4-dimethoxyphenyl)-2-(2-methoxyphenoxy)-l,3- propanediol (2g). This compound was prepared according to a literature procedure. (Buendia, J. ; (0181) Mottweiler, J.; Bolm, C. Chem. Eur. J. 2011, 17, 13877.) Spectral data were consistent with those reported in the literature. *H NMR (400 MHz, CDC13) delta 7.07 (ddd, J = 8.2 Hz, 7.2, 1.6, 1.6 Hz, 1H), 7.02-6.84 (M, 5H), 6.82 (D, J = 8.2 Hz, 1H), 4.98 (b t, J = 4.8 Hz, 1 H), 4.16 (ddd, J = 6.0, 4.8, 3.5 Hz, 1 H), 3.95-3.90 (m, 1H), 3.87 (s, 3H), 3.86 (s, 6H), 3.66 (ddd, J = 12.0, 7.2, 3.5 Hz, 1H), 2.87 ppm (b s, 1H). HRMS (EI) calculated for C18H2206Na [M + Na]+ 357.1314, found 357.1311.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 94687-10-2, Ethyl 3-(3,4-dimethoxyphenyl)-3-hydroxy-2-(2-methoxyphenoxy)propanoate.

Reference:
Patent; WISCONSIN ALUMNI RESEARCH FOUNDATION; STAHL, Shannon, S.; COON, Joshua; RAHIMI, Alireza; ULBRICH, Arne; WO2015/138563; (2015); A1;,
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