A new synthetic route of 303043-91-6

The chemical industry reduces the impact on the environment during synthesis 303043-91-6, I believe this compound will play a more active role in future production and life.

Synthetic Route of 303043-91-6, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.303043-91-6, name is 3-Fluoro-2-methoxybenzenemethanol, molecular formula is C8H9FO2, molecular weight is 156.1543, as common compound, the synthetic route is as follows.

a 1-(Chloromethyl)-3-fluoro-2-methoxy-benzene A solution of 3-fluoro-2-methoxy-benzenemethanol (WO 20000419) (0.50 g) and thionyl chloride (0.47 ml) in dichloromethane (30 ml) was stirred for 2 hours then concentrated in-vacuo to give the subtitled compound, which was used directly in the next step.

The chemical industry reduces the impact on the environment during synthesis 303043-91-6, I believe this compound will play a more active role in future production and life.

Reference:
Patent; Bonnert, Roger; Gardiner, Stewart; Hunt, Fraser; Walters, Iain; US2003/55250; (2003); A1;,
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