Some scientific research about 404-91-1

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 404-91-1, 2-(3-Fluoro-4-methoxyphenyl)ethanol.

404-91-1, Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 404-91-1, name is 2-(3-Fluoro-4-methoxyphenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows.

A mixture of resin bound triphenyl phosphine (polystyrene 2% cross linking, loading = 3 mmol/g, 3 g, 9 mmol) and imidazole (0.48 g, 7.1 mmol) in DCM (30 ml.) cooled on an ice bath was drop wise added Br2 (1.13 g, 7.1 mmol), whereupon a solution of 4-(2-hydroxy- ethyl)-2-fluoro-1-methoxy-benzene (1.0g, 5.88 mmol) in DCM (5 ml.) was added. The cooling bath was removed and the reaction mixture was stirred for 16 hs before the resin was filtered off. The resin was washed with DCM and the filtrate was concentrated in vacuo. The residue was purified using column chromatography (SiO2, heptane-EtAOc 95:5) to give 0.82 g of 4- (2-bromo-ethyl)-2-fluoro-1-methoxy-benzene

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 404-91-1, 2-(3-Fluoro-4-methoxyphenyl)ethanol.

Reference:
Patent; NOVO NORDISK A/S; WO2008/84044; (2008); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts