Category: 23002-78-0

The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-Methylthiazol-4-yl)ethanone(SMILESS: CC(C1=CSC(C)=N1)=O,cas:23002-78-0) is researched.Application of 4221-99-2. The article 《Structure-based design, synthesis, and biological evaluation of dihydroquinazoline-derived potent β-secretase inhibitors》 in relation to this compound, is published in Bioorganic & Medicinal Chemistry Letters. Let’s take a look at the latest research on this compound (cas:23002-78-0).

Structure-based design, synthesis, and biol. evaluation of a series of 2-amino-3,4-dihydroquinazoline-derived β-secretase inhibitors incorporating thiazole and pyrazole-derived P2-ligands are described. One inhibitor showed potent enzyme inhibitory (Ki = 13 nM) and cellular (IC50 = 21 nM in neuroblastoma cells) assays. The model of this compound suggested possible interactions in the active site.

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Application of 23002-78-0. The fused heterocycle is formed by combining a benzene ring with a single heterocycle, or two or more single heterocycles. Compound: 1-(2-Methylthiazol-4-yl)ethanone, is researched, Molecular C6H7NOS, CAS is 23002-78-0, about Heterocycles from amino ketones. XIV. Thiazolyl- and pyrrolylquinolines. Author is Kempter, Gerhard; Schaefer, Harry; Sarodnick, Gerhard.

2-(R-Substituted)-4-(R1-substituted)-quinolines (I) [where R = 2-methylthiazol-4-yl (II), 2-phenylthiazol-4-yl, 2,4-dimethylthiazol-5-yl, 2-phenyl-4-methylthiazol-5-yl, 2-amino-4-methylthiazol-5-yl, or 2-pyrryl (III); and R1 = Me or Ph] were prepared by the method of K. et al. (1964). I showed pronounced fluorescence and were tested as fluorescence indicators. Reaction of MeCSNH2 with BrCH2COC(NOH)Me gave 2-methyl-4-acetylthiazole-3-oxime, which was saponified to 2-methyl-4-acetylthiazole.

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The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-Methylthiazol-4-yl)ethanone(SMILESS: CC(C1=CSC(C)=N1)=O,cas:23002-78-0) is researched.COA of Formula: C8H12Cl2Pt. The article 《Heterocycles from amino ketones. XIV. Thiazolyl- and pyrrolylquinolines》 in relation to this compound, is published in Zeitschrift fuer Chemie. Let’s take a look at the latest research on this compound (cas:23002-78-0).

2-(R-Substituted)-4-(R1-substituted)-quinolines (I) [where R = 2-methylthiazol-4-yl (II), 2-phenylthiazol-4-yl, 2,4-dimethylthiazol-5-yl, 2-phenyl-4-methylthiazol-5-yl, 2-amino-4-methylthiazol-5-yl, or 2-pyrryl (III); and R1 = Me or Ph] were prepared by the method of K. et al. (1964). I showed pronounced fluorescence and were tested as fluorescence indicators. Reaction of MeCSNH2 with BrCH2COC(NOH)Me gave 2-methyl-4-acetylthiazole-3-oxime, which was saponified to 2-methyl-4-acetylthiazole.

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The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: 1-(2-Methylthiazol-4-yl)ethanone( cas:23002-78-0 ) is researched.Safety of 1-(2-Methylthiazol-4-yl)ethanone.Shafiee, A.; Anaraki, M.; Bazzaz, A. published the article 《Selenium heterocycles. XXXVII. Synthesis of 4-(thiazol-4-yl)-1,2,3-selenadiazoles and 4-(selenazol-4-yl)-1,2,3-selenadiazoles》 about this compound( cas:23002-78-0 ) in Journal of Heterocyclic Chemistry. Keywords: formylthiazole conversion thiazolylselnadiazole; formylselenazole conversion selenazolylselenadiazole; thiazolylselenadiazole preparation conversion diselenafulvene; thiaselenole thiazolylthioxo; carbon disulfide reaction thiazolylselenadiazole. Let’s learn more about this compound (cas:23002-78-0).

Starting from readily available 2-substituted-4-formylthiazoles and selenazoles, a series of selenazolylselenadiazoles I (R = e.g. Ph, 4-MeOC6H4, 4-BrC6H4; X = Se) and thiazolylselenadiazoles I (X = S) were prepared Pyrolysis of compound I (X = S) afforded thiazolylacetylenes II. Addition of KOH pellets to an alc. solution of I (X = S) gave diselenafulvenes III. Decomposition of compound I (X = S) with base followed by the addition of CS2 gave thiazolylthioxothiaselenoles IV.

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Ghosh, Arun K.; Pandey, Satyendra; Gangarajula, Sudhakar; Kulkarni, Sarang; Xu, Xiaoming; Rao, Kalapala Venkateswara; Huang, Xiangping; Tang, Jordan published an article about the compound: 1-(2-Methylthiazol-4-yl)ethanone( cas:23002-78-0,SMILESS:CC(C1=CSC(C)=N1)=O ).SDS of cas: 23002-78-0. Aromatic heterocyclic compounds can be classified according to the number of heteroatoms or the size of the ring. The authors also want to convey more information about this compound (cas:23002-78-0) through the article.

Structure-based design, synthesis, and biol. evaluation of a series of 2-amino-3,4-dihydroquinazoline-derived β-secretase inhibitors incorporating thiazole and pyrazole-derived P2-ligands are described. One inhibitor showed potent enzyme inhibitory (Ki = 13 nM) and cellular (IC50 = 21 nM in neuroblastoma cells) assays. The model of this compound suggested possible interactions in the active site.

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Heterocyclic compounds can be divided into two categories: alicyclic heterocycles and aromatic heterocycles. Compounds whose heterocycles in the molecular skeleton cannot reflect aromaticity are called alicyclic heterocyclic compounds. Compound: 23002-78-0, is researched, Molecular C6H7NOS, about The synthesis of 2-(heteroaryl)imidazo[1,2-a]pyridin-3-ols and related compounds, the main research direction is imidazopyridinol; imidazopyrimidine; imidazophthalazine; pyridinamine oxide cyclization bromoacetyl heterocycle.Application In Synthesis of 1-(2-Methylthiazol-4-yl)ethanone.

A reaction between pyridin-2-amine 1-oxides and bromoacetyl heteroaromatic compounds gave the title compounds,e.g., I. The reaction of some 2-aminodiazine 1-oxides with phenacyl bromides was also studied. The imidazo[1,2-a]pyrimidine and imidazo[2,1-a]phthalazine systems were prepared but reaction of pyrazin-2-amine 1-oxide did not give the desired cyclization.

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The reaction of an aromatic heterocycle with a proton is called a protonation. One of articles about this theory is 《Lipase kinetic enantiomeric resolution of 1-heteroarylethanols》. Authors are Kucher, Olexandr V.; Kolodyazhnaya, Anastasiya O.; Smolii, Oleg B.; Nazarenko, Nadiya K.; Kubyshkin, Vladimir; Mykhailiuk, Pavel K.; Tolmachev, Andrey A..The article about the compound:1-(2-Methylthiazol-4-yl)ethanonecas:23002-78-0,SMILESS:CC(C1=CSC(C)=N1)=O).Quality Control of 1-(2-Methylthiazol-4-yl)ethanone. Through the article, more information about this compound (cas:23002-78-0) is conveyed.

The use of lipases offers a simple and straightforward method toward various chiral secondary alcs. Here we examined the lipase resolution of 1-heteroarylethanols. Racemic substrates were subjected to a two step resolution strategy. The difference between the substituent sizes around the chiral fragment allowed the successful isolation of the (S)-alcs. with assistance of the Burkholderia cepacia lipase (ee ≥ 96%). The (R)-isomers were obtained after hydrolysis of the enantioenriched O-acetylated alcs. either with Candida antarctica lipase B or with potassium carbonate. The performance of the latter step was found to be substrate dependent.

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The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-Methylthiazol-4-yl)ethanone(SMILESS: CC(C1=CSC(C)=N1)=O,cas:23002-78-0) is researched.Product Details of 438630-64-9. The article 《Selenium heterocycles. XXXVII. Synthesis of 4-(thiazol-4-yl)-1,2,3-selenadiazoles and 4-(selenazol-4-yl)-1,2,3-selenadiazoles》 in relation to this compound, is published in Journal of Heterocyclic Chemistry. Let’s take a look at the latest research on this compound (cas:23002-78-0).

Starting from readily available 2-substituted-4-formylthiazoles and selenazoles, a series of selenazolylselenadiazoles I (R = e.g. Ph, 4-MeOC6H4, 4-BrC6H4; X = Se) and thiazolylselenadiazoles I (X = S) were prepared Pyrolysis of compound I (X = S) afforded thiazolylacetylenes II. Addition of KOH pellets to an alc. solution of I (X = S) gave diselenafulvenes III. Decomposition of compound I (X = S) with base followed by the addition of CS2 gave thiazolylthioxothiaselenoles IV.

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The three-dimensional configuration of the ester heterocycle is basically the same as that of the carbocycle. Compound: 1-(2-Methylthiazol-4-yl)ethanone(SMILESS: CC(C1=CSC(C)=N1)=O,cas:23002-78-0) is researched.Category: thiazolidine. The article 《Heterocycles from amino ketones. XIV. Thiazolyl- and pyrrolylquinolines》 in relation to this compound, is published in Zeitschrift fuer Chemie. Let’s take a look at the latest research on this compound (cas:23002-78-0).

2-(R-Substituted)-4-(R1-substituted)-quinolines (I) [where R = 2-methylthiazol-4-yl (II), 2-phenylthiazol-4-yl, 2,4-dimethylthiazol-5-yl, 2-phenyl-4-methylthiazol-5-yl, 2-amino-4-methylthiazol-5-yl, or 2-pyrryl (III); and R1 = Me or Ph] were prepared by the method of K. et al. (1964). I showed pronounced fluorescence and were tested as fluorescence indicators. Reaction of MeCSNH2 with BrCH2COC(NOH)Me gave 2-methyl-4-acetylthiazole-3-oxime, which was saponified to 2-methyl-4-acetylthiazole.

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In general, if the atoms that make up the ring contain heteroatoms, such rings become heterocycles, and organic compounds containing heterocycles are called heterocyclic compounds. An article called Selenium heterocycles. XXXVII. Synthesis of 4-(thiazol-4-yl)-1,2,3-selenadiazoles and 4-(selenazol-4-yl)-1,2,3-selenadiazoles, published in 1986-06-30, which mentions a compound: 23002-78-0, Name is 1-(2-Methylthiazol-4-yl)ethanone, Molecular C6H7NOS, Product Details of 23002-78-0.

Starting from readily available 2-substituted-4-formylthiazoles and selenazoles, a series of selenazolylselenadiazoles I (R = e.g. Ph, 4-MeOC6H4, 4-BrC6H4; X = Se) and thiazolylselenadiazoles I (X = S) were prepared Pyrolysis of compound I (X = S) afforded thiazolylacetylenes II. Addition of KOH pellets to an alc. solution of I (X = S) gave diselenafulvenes III. Decomposition of compound I (X = S) with base followed by the addition of CS2 gave thiazolylthioxothiaselenoles IV.

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