Category: 2612-28-4

As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 2612-28-4, name is 2-Propylpropane-1,3-diol, molecular formula is C6H14O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Application In Synthesis of 2-Propylpropane-1,3-diol

(2-1) under a nitrogen atmosphere, 4-bromo-3-fluorobenzaldehyde (20.0g), 2- propyl-1,3-propanediol (11.6g) and p-toluenesulfonic acid monohydrate (0.9g ) was dissolved in toluene (100mL), while using the Dean-Stark apparatus at reflux of the solvent while removing the formed water was stirred for 4 hours. After cooling, saturated aqueous sodium bicarbonate solution (100 mL) were separated, washed with saturated brine (100 mL) and the organic layer was washed, dried over anhydrous sodium sulfate. The solvent was distilled off under reduced pressure, the residue was purified by silica gel column chromatography was purified to give crude 2- (4-bromo-3-fluorophenyl) -5-propyl-1,3-dioxane (31.0g) .

With the rapid development of chemical substances, we look forward to future research findings about 2612-28-4.

Reference:
Patent; DIC Corporation; Tojo, Kenta; Tetsuo, Kusumoto; (46 pag.)CN105358538; (2016); A;,
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Electric Literature of 2612-28-4, With the rapid development and complex challenges of chemical substances, the synthesis of new drugs is usually one of the most effective ways to increase yield.2612-28-4, name is 2-Propylpropane-1,3-diol, molecular formula is C6H14O2, molecular weight is 118.17, as common compound, the synthetic route is as follows.

EXAMPLE 21 According to Scheme II given above 1-(4-chloro-3-fluorophenyl)-2-(4-(5-propyldioxane-2-yl)-phenyl)-ethane is obtained from 1-(4-chloro-3-fluorophenyl)-2-(4-bromophenyl)-ethane and 2-(hydroxymethyl)-pentan-1-ol.

Statistics shows that 2612-28-4 is playing an increasingly important role. we look forward to future research findings about 2-Propylpropane-1,3-diol.

Reference:
Patent; Merck Patent Gesellschaft mit beschrankter Haftung; US5254698; (1993); A;,
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In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2612-28-4, name is 2-Propylpropane-1,3-diol, the common compound, a new synthetic route is introduced below. Recommanded Product: 2-Propylpropane-1,3-diol

3rd Step 2-Propyl-1,3-propanediol 17.4 g (147 mol) and the above 3-(4-trifluoromethylphenyl)propanal 20.0 g (98.9 mmol) were dissolved in toluene 200 ml, and PTS 1 g was added, and the mixture was refluxed with heating for 3 hours while removing water formed with Dien-Stark. The reactant was washed with a saturated sodium bicarbonate aqueous solution, and then with saturated sodium chloride aqueous solution, and dried over anhydrous magnesium sulfate, and the solvent was distilled off. The residue was purified by silica gel column chromatography (eluent: toluene), and recrystallized twice from ethanol to obtain 5-propyl-2-(2-(4-trifluoromethylphenyl)ethyl)-1,3-dioxane 10.8 g (35.7 mmol). The yield was 36.1% from 3-(4-trifluoromethylphenyl) propanal. 1H-NMR(CDCl3) delta(ppm): 7.41 (dd,4H), 4.41(t,1H), 4.18-4.00(m,2H), 3.41-3.16(m,2H), 2.88-2.70(m,2H), 2.14-1.80(m,3H), 1.35-0.81(m,7H)

The synthetic route of 2612-28-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; Chisso Corporation; US6235355; (2001); B1;,
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Application of 2612-28-4, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 2612-28-4, name is 2-Propylpropane-1,3-diol, molecular formula is C6H14O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

EXAMPLE 5 A mixture of 1.2 g of 2-propylpropane-1,3-diol, 2.59 g of 5-(2-pentyl-5-pyridyl)-2-formyl-thiophene (obtainable by formylation of 5-(2-pentyl-5-pyridyl)-thiophene via a Vilsmeier reaction), 0.01 g of p-toluenesulfonic acid and 15 ml of toluene is boiled for 3 hours, using a water separator, cooled, washed with water and evaporated. 5-(2-Pentyl-5-pyridyl)-2-(trans-5-propyl-1,3-dioxan-2-yl)-thiophene is obtained.

According to the analysis of related databases, 2612-28-4, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Merck Patent Gesellschaft Mit Beschrankter Huftung; US4659503; (1987); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 2612-28-4, name is 2-Propylpropane-1,3-diol. This compound has unique chemical properties. The synthetic route is as follows. Formula: C6H14O2

(2-1) In a nitrogen atmosphere, 4-bromo-3-fluorobenzalde- hyde (20.0 g), 2-propyl-1 ,3-propanediol (11.6 g), and p-toluenesulfonic acid monohydrate (0.9 g) were dissolved in toluene (100 mE), and the resulting solution was stirred for four hours under solvent refluxing while removing generated water with a Dean-Stark apparatus. Afier the mixture was left to cool, a saturated aqueous sodium hydrogen carbonate solution (100 mE) was added thereto to conduct separation, and the organic layer was washed with saturated saline (100 mE) and dried by addition of anhydrous sodium sulfate. Afier the solvent was distilled away at a reduced pressure, the residue was purified by silica gel colunm chromatography. As a result, crude 2-(4-bromo-3-fluorophenyl)-5-propyl- 1 ,3-di- oxane (31.0 g) was obtained.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 2612-28-4, 2-Propylpropane-1,3-diol.

Reference:
Patent; DIC CORPORATION; Tojo, Kenta; Kusumoto, Tetsuo; (36 pag.)US2016/159765; (2016); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Electric Literature of 2612-28-4 ,Some common heterocyclic compound, 2612-28-4, molecular formula is C6H14O2, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

EXAMPLE B A mixture of 2.3 g of trans-4-(4-cyano-3-fluorophenyl)-cyclohexanecarbaldehyde, 1.2 g of 2-propylpropane-1,3-diol, 0.01 g of p-toluenesulfonic acid and 15 ml of toluene is boiled for 3 hours under a water separator and is cooled. Working up in the customary manner gives 2-[trans-4-(4-cyano-3-fluorophenyl)-cyclohexyl]-5-propyl-1,3-dioxane.

In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2612-28-4, 2-Propylpropane-1,3-diol, other downstream synthetic routes, hurry up and to see.

Reference:
Patent; Merck Patent Gesellschaft Mit Beschrankter Haftung; US4784471; (1988); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts