Synthetic Route of 136-80-1, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 136-80-1, name is N-(2-Hydroxyethyl)-2-methylaniline, molecular formula is C9H13NO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
This embodiment provides a quinone compound, and its reaction formula is:In a reaction flask, 5 mmol of N-hydroxyethyl-2-methylaniline and 7.5 mmol of 2-methylaniline provided in Example 2 were weighed out and dissolved in 200 ml of acetonitrile, and Sn/activated carbon loaded catalyst was added, and TLC was used to detect N. The reaction was stopped after the reaction of hydroxyethyl-2-methylaniline was completed.After isolation and purification, 7-methylindole was obtained (yield 64.3%).
According to the analysis of related databases, 136-80-1, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Chongqing Huage Biochemical Co., Ltd.; He Xiaoqiang; Chen Zhizhong; Wu Chengli; (8 pag.)CN107445881; (2017); A;,
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