Category: 6006-82-2

Application of 6006-82-2, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 6006-82-2, name is 2-(Benzo[d][1,3]dioxol-5-yl)ethanol, molecular formula is C9H10O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.

B. 1-acetoxy-2-[(3,4-methylenedioxy)phenyl]ethane To a stirred solution of 2-(3,4-methylenedioxy)phenyl-1-ethanol (1.68 g, 10 mmol) in dry pyridine was added acetic anhydride and the resultant reaction mixture was stirred at 80 C. for 1 h. The reaction mixture was poured into ice-water and was extracted with ether (2*75 ml). The combined ether extract was washed with water (2*50 ml), 5% HCl (2*50 ml) and then with 5% NaHCO3 (2*50 ml). The organic layer was dried over magnesium sulfate and the solvent was removed under reduced pressure to give 1-acetoxy-2-[(3,4-methylenedioxy)phenyl]ethane as a solid (1.7 g, 81% yield).

According to the analysis of related databases, 6006-82-2, the application of this compound in the production field has become more and more popular.

Reference:
Patent; Texas Biotechnology Corporation; US6432994; (2002); B1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Adding a certain compound to certain chemical reactions, such as: 6006-82-2, 2-(Benzo[d][1,3]dioxol-5-yl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 2-(Benzo[d][1,3]dioxol-5-yl)ethanol, blongs to alcohols-buliding-blocks compound. name: 2-(Benzo[d][1,3]dioxol-5-yl)ethanol

B. 1-Acetoxy-2-[(3,4-methylenedioxy)phenyl]ethane To a stirred solution of 2-(3,4-methylenedioxy)phenyl-1-ethanol (1.68 g, 10 mmol) in dry pyridine was added acetic anhydride and the resultant reaction mixture was stirred at 80 C. for 1h. The reaction mixture was poured into ice-water and was extracted with ether (2*75 mL). The combined ether extract was washed with water (2*50 ml), 5% Hcl (2*50 mL) and then with 5% NaHCO3 (2*50 mL). The organic layer was dried over magnesium sulfate and the solvent was removed under reduced pressure to give 1-acetoxy-2-[(3,4-methylenedioxy)phenyl]ethane as a solid (1.7 g, 81% yield).

At the same time, in my other blogs, there are other synthetic methods of this type of compound,6006-82-2, 2-(Benzo[d][1,3]dioxol-5-yl)ethanol, and friends who are interested can also refer to it.

Reference:
Patent; Texas Biotechnology Corp.; US6248767; (2001); B1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts