Category: 52010-89-6

The persulfate oxidation of phenols and arylamines (the Elbs and the Boyland-Sims oxidations) was written by Behrman, E. J.. And the article was included in Organic Reactions (Hoboken, NJ, United States) in 1988.Synthetic Route of C8H8O3 The following contents are mentioned in the article:

A review of the article The persulfate oxidation of phenols and arylamines (the Elbs and the Boyland-Sims oxidations). This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Synthetic Route of C8H8O3).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Synthetic Route of C8H8O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Total synthesis of the fungal metabolite (±)-acremine G: acceleration of a biomimetic Diels-Alder reaction on silica gel was written by Mehta, Goverdhan;Babu Khan, Tabrez;Sunil Kumar, Y. C.. And the article was included in Tetrahedron Letters in 2010.Recommanded Product: 52010-89-6 The following contents are mentioned in the article:

A total synthesis of the bioactive tetracyclic natural product acremine G has been achieved in which a regio- and stereoselective biomimetic Diels-Alder reaction between two readily assembled building blocks, accelerated on a solid support (silica gel), forms the key step. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Recommanded Product: 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. A strong base can deprotonate an alcohol to yield an alkoxide ion (R―O−). For example, sodamide (NaNH2), a very strong base, abstracts the hydrogen atom of an alcohol. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.Recommanded Product: 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A vicarious, one-pot synthesis of benzo- and naphthofurans: Applications to the syntheses of stereumene B and paeoveitols was written by Rashid, Showkat;Bhat, Bilal A.;Mehta, Goverdhan. And the article was included in Tetrahedron Letters in 2019.Reference of 52010-89-6 The following contents are mentioned in the article:

An interesting albeit unexpected deviation during attempted Tanabe γ-lactone annulation on 4-hydroxycyclohexanones has led to a general, one-pot synthesis of benzofurans and naphtho[2,3-b]furans from readily assembled precursors. The utility of this adaptable methodol. has been demonstrated through concise syntheses of natural products, stereumene B, paeoveitol D and (±)-paeoveitol. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Reference of 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Reference of 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Synthesis of novel isoxazole-benzoquinone hybrids via 1,3-dipolar cycloaddition reaction as key step was written by Ravi Kumar, P.;Behera, Manoranjan;Raghavulu, K.;Jaya Shree, A.;Yennam, Satyanarayana. And the article was included in Tetrahedron Letters in 2012.Category: alcohols-buliding-blocks The following contents are mentioned in the article:

An efficient method for the preparation of novel 2-(5-arylisoxazol-3-yl)cyclohexa-2,5-diene-1,4-dione hybrids via 1,3-dipolar cycloaddition followed by an oxidation reaction using ceric ammonium nitrate (CAN) has been described. Using this method, various aryl as well as alkyl substituted isoxazole-benzoquinone hybrids were synthesized in high yields. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Category: alcohols-buliding-blocks).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Category: alcohols-buliding-blocks

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Hallucinogens. IV. Synthesis of 2,5-dimethoxy-4-methylamphetamine was written by Ono, Masako;Shimamine, Mochihiko;Takahashi, Kazunori. And the article was included in Eisei Shikensho Hokoku in 1973.Related Products of 52010-89-6 The following contents are mentioned in the article:

2,5-Dimethoxy-4-methylamphetamine (I) was prepared The J. C. Duff method was improved to give 2-hydroxy-4-methylbenzaldehyde from m-cresol and hexamine; the reaction temperature was 140°. 2,5-Dihydroxy-4-methylbenzaldehyde (II) was obtained by the J. Renz method and methylation of II with Me2SO4 in alk. solution afforded 2,5-dimethoxy-4-methylbenzaldehyde (III). Reaction of III with EtNO2 in the presence of AcONH4 gave 1-(2,5-dimethoxy-4-methylphenyl)-2-nitropropene (IV). Reduction of IV with LiAlH4 afforded I and its hydrochloride. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Related Products of 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Related Products of 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

A Total Synthesis of Paeoveitol was written by Xu, Lun;Liu, Fengyi;Xu, Li-Wen;Gao, Ziwei;Zhao, Yu-Ming. And the article was included in Organic Letters in 2016.HPLC of Formula: 52010-89-6 The following contents are mentioned in the article:

A four-step total synthesis of paeoveitol (I), a recently disclosed norditerpene natural product from Paeonia vetchii, is reported. This highly concise synthetic route was guided by biosynthetic considerations and enabled by an unusual intermol. ortho-quinone methide [4 + 2]-cycloaddition reaction, which proceeded with excellent regio- and diastereoselectivity. D. functional theory (DFT) calculations point to a crucial intermol. hydrogen bond and π-π stacking interaction that govern selectivity in this process. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6HPLC of Formula: 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.HPLC of Formula: 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Molecular docking study, synthesis and evaluation of antitumor activity of novel pyrazole derivatives was written by Jebastin, J. Nelson Samuel;Kumar, T. Ramesh;Evangelin, D.. And the article was included in International Journal of Pharmaceutical and Chemical Sciences in 2016.HPLC of Formula: 52010-89-6 The following contents are mentioned in the article:

A series of (benzylideneamino)phenyl-1H-pyrazol-3(2H)-one derivatives I [R = 3-Me, 3,6-(OH)₂, 2,4,6-(NH₂)₃, etc.] was synthesized via condensation of 4-aminoantipyrine with benzaldehydes. All the synthesized compounds were evaluated for for their ability to inhibit cell proliferation in cancer cell lines and tested in silico for their interaction with histone deacetylase (HDAC8) enzyme. Based on the docking score, compound I [R = 3-Br-6-OH] showed highest docking score of -6.4061, which is important for HDAC8 inhibition. Among the synthesized compounds, compound I [R = 3-Br-6-OH] showed promising activity against human cervical cancer cell line. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6HPLC of Formula: 52010-89-6).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.HPLC of Formula: 52010-89-6

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Feasibility of Laminaria japonica as a feedstock for fast pyrolysis in a bubbling fluidized-bed reactor was written by Choi, Jae-Wook;Choi, Jong Ho;Suh, Dong Jin;Kim, Hwayong. And the article was included in Journal of Analytical and Applied Pyrolysis in 2015.Electric Literature of C8H8O3 The following contents are mentioned in the article:

Laminaria japonica, brown algae, was used as a feedstock for fast pyrolysis in a bubbling fluidized-bed (BFB) reactor by manipulating the pyrolysis temperature, feeding rate, and ratio of the fluidizing velocity to the min. fluidizing velocity (U/U_mf), which exhibited optimum operating conditions of a feeding rate of 600 g/h, a U/U_mf of 18.3 and a pyrolysis temperature of 425°C. The maximum yield of L. japonica-derived bio-oil (approx. 35 weight %) was lower than that of lignocellulose. When fractionated, the L. japonica-derived bio-oil was found to be composed of several major compounds, including cyclic aliphatic compounds, which were very different from aromatic mols., the major compounds of lignocellulose-derived bio-oil. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Electric Literature of C8H8O3).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Electric Literature of C8H8O3

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts

Evaluation of HIV-1 inhibition by stereoisomers and analogues of the sesquiterpenoid hydroquinone peyssonol A was written by Treitler, Daniel S.;Li, Zhufang;Krystal, Mark;Meanwell, Nicholas A.;Snyder, Scott A.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Name: 2,5-Dihydroxy-4-methylbenzaldehyde The following contents are mentioned in the article:

Peyssonol A, a brominated natural product with documented anti-HIV-1 activity, was synthesized racemically along with 6 isomers and 15 truncated analogs and synthetic precursors. These compounds were screened in a cell-based assay against a recombinant HIV-1 strain to investigate structure-activity relationships. The results obtained suggest that both the aliphatic and aromatic domains of peyssonol A are responsible for its potency, while the stereochem. configuration of the substituents on the aliphatic domain, including their bromine atom, are largely irrelevant. Although none of the analogs tested were as potent as the parent natural product, several exhibited greater therapeutic indexes due to reduced cytotoxicity, noting that nearly all compounds tested were measurably cytotoxic. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Name: 2,5-Dihydroxy-4-methylbenzaldehyde).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: 2,5-Dihydroxy-4-methylbenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts