Treitler, Daniel S. et al. published their research in Bioorganic & Medicinal Chemistry Letters in 2013 | CAS: 52010-89-6

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: 2,5-Dihydroxy-4-methylbenzaldehyde

Evaluation of HIV-1 inhibition by stereoisomers and analogues of the sesquiterpenoid hydroquinone peyssonol A was written by Treitler, Daniel S.;Li, Zhufang;Krystal, Mark;Meanwell, Nicholas A.;Snyder, Scott A.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2013.Name: 2,5-Dihydroxy-4-methylbenzaldehyde The following contents are mentioned in the article:

Peyssonol A, a brominated natural product with documented anti-HIV-1 activity, was synthesized racemically along with 6 isomers and 15 truncated analogs and synthetic precursors. These compounds were screened in a cell-based assay against a recombinant HIV-1 strain to investigate structure-activity relationships. The results obtained suggest that both the aliphatic and aromatic domains of peyssonol A are responsible for its potency, while the stereochem. configuration of the substituents on the aliphatic domain, including their bromine atom, are largely irrelevant. Although none of the analogs tested were as potent as the parent natural product, several exhibited greater therapeutic indexes due to reduced cytotoxicity, noting that nearly all compounds tested were measurably cytotoxic. This study involved multiple reactions and reactants, such as 2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6Name: 2,5-Dihydroxy-4-methylbenzaldehyde).

2,5-Dihydroxy-4-methylbenzaldehyde (cas: 52010-89-6) belongs to alcohols. The oxygen atom of the strongly polarized O―H bond of an alcohol pulls electron density away from the hydrogen atom. This polarized hydrogen, which bears a partial positive charge, can form a hydrogen bond with a pair of nonbonding electrons on another oxygen atom. Alcohols may be oxidized to give ketones, aldehydes, and carboxylic acids. These functional groups are useful for further reactions. Oxidation of organic compounds generally increases the number of bonds from carbon to oxygen (or another electronegative element, such as a halogen), and it may decrease the number of bonds to hydrogen.Name: 2,5-Dihydroxy-4-methylbenzaldehyde

Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts