Application of 626-18-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 626-18-6, name is 1,3-Benzenedimethanol. This compound has unique chemical properties. The synthetic route is as follows.
1,3-phenylenedimethanol (2.18 g, 15.778 mmol) was dissolved in DMF (21.80 ml) and cooled to 0 C, Imidazole (2.148 g, 31.557 mmol) was added followed by the addition of tert-Butyldimethylchlorosilane (2.378 g, 15.778 mmol). The mixture was stirred at 0 C for 1 h and allowed to warm up to r.t. and stirred overnight. Upon completion of the reaction, the mixture was quenched with sat. aq. NH4C1 (10 ml), extracted with EtOAc (2 x 100 ml). The organic layer was washed with sat. aq. NaHC03solution (10 ml), dried over Na2S04and concentrated. The residue was purified by flash chromatography to give (3-(((tert-butyldimethylsilyl)oxy)methyl)phenyl)methanol (393) as colorless oil (1.73 g, 43.4% yield)
According to the analysis of related databases, 626-18-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; EISAI R&D MAN CO LTD; E Ja I Al Aendeu D Maenijimeonteu Gabu Siki Ga I Sya; ZHENG WANJUN; Jaeng , -wan-jun; ZHU XIAOJIE; Ju , -sya-o-ji-e; DU HONG; Du , -hong; POSTEMA MAARTEN; Po Seu-te-ma-, -ma-a-reu-ten; JIANG YIMIN; Jang , -w-min; LI JING; Ri , -jing; YU ROBERT; Yu , -ro-beo-teu; CHOI HYEONG WOOK; Choe , -hyeong—uk; LEE JAEMOON; I , -jae-mun; FANG FRANK; Paeng , -peu-rang-keu; CUSTAR DANIEL; Ku Seu-ta-, -da-ni-el; (178 pag.)KR2018/83863; (2018); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts