Synthetic Route of 6214-44-4, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 6214-44-4, name is (4-Ethoxyphenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
Under an argon stream, p-Ethoxybenzyl alcohol (1) (6.509, 42.7 mmol) Of anhydrous methylene chloride (90 mL), The mixed solution of anhydrous N, N-dimethylformamide (70 L) was cooled with ice, Thionyl chloride (4.0 mL, 55.7 mmol) was added, And stirred for 30 minutes. The reaction solution was concentrated and dissolved in tetrahydrofuran (30 mL) Was added dropwise to ice water (150 mL). It was extracted twice with methylene chloride (50 mL) The obtained organic layer was dried with sodium sulfate, By concentrating under reduced pressure, To give compound 2 (7.66 g) as a pale yellow liquid.
According to the analysis of related databases, 6214-44-4, the application of this compound in the production field has become more and more popular.
Reference:
Patent; ST. MARIANNA UNIVERSITY SCHOOL OF MEDICINE; DOKKYO GAKUEN DOKKYO UNIVERSITY SCHOOL OF MEDICINE; MATSUMOTO, NOBUYUKI; ANZAI, NAOHIKO; (16 pag.)JP2018/62475; (2018); A;,
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