The enantioselective reduction of 2′-fluoroacetophenone utilizing a simplified CBS-reduction procedure was written by Garrett, Christine E.;Prasad, Kapa;Repic, Oljan;Blacklock, Thomas J.. And the article was included in Tetrahedron: Asymmetry in 2002.HPLC of Formula: 171032-87-4 This article mentions the following:
A practical, non-enzymic, catalytic process was developed for the enantioselective reduction of 2′-fluoroacetophenone. A number of catalysts were screened for the oxazaborolidine-type reduction of this ketone to obtain an optimized system. It was shown that the simplest procedure uses the catalyst formed in situ from (S)-α,α-diphenyl-2-pyrrolidinemethanol and borane-diethylaniline. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4HPLC of Formula: 171032-87-4).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. The most common reactions of alcohols can be classified as oxidation, dehydration, substitution, esterification, and reactions of alkoxides.HPLC of Formula: 171032-87-4
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts