SDS of cas: 7661-33-8. The reaction of aromatic heterocyclic molecules with protons is called protonation. Aromatic heterocycles are more basic than benzene due to the participation of heteroatoms. Compound: 1-(4-Chlorophenyl)pyrrolidin-2-one, is researched, Molecular C10H10ClNO, CAS is 7661-33-8, about Mild and Efficient Cobalt-Catalyzed Cross-Coupling of Aliphatic Amides and Aryl Iodides in Water. Author is Tan, Bryan Yong-Hao; Teo, Yong-Chua.
A convenient protocol for the C-N cross-coupling of aliphatic amides and iodobenzene is demonstrated using a simple and inexpensive Co(C2O4)·2H2O/N,N’-dimethylethylenediamine (DMEDA) catalytic system in water. Good yields of N-arylated products I [R1 = Pr, i-Pr, Bu, etc; R2 = Ph, 2-F-C6H4, 4-Me-C6H4, etc.] were isolated (up to 85%) and the protocol has been successfully applied to the synthesis of the anticancer drug, flutamide.
Although many compounds look similar to this compound(7661-33-8)SDS of cas: 7661-33-8, numerous studies have shown that this compound(SMILES:O=C1N(C2=CC=C(Cl)C=C2)CCC1), has unique advantages. If you want to know more about similar compounds, you can read my other articles.
Reference:
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