The Absolute Best Science Experiment for 77903-28-7

There is still a lot of research devoted to this compound(SMILES:COC1=C(C)C(N)=CN=C1)Electric Literature of C7H10N2O, and with the development of science, more effects of this compound(77903-28-7) can be discovered.

In organic chemistry, atoms other than carbon and hydrogen are generally referred to as heteroatoms. The most common heteroatoms are nitrogen, oxygen and sulfur. Now I present to you an article called Discovery of Azetidinyl Ketolides for the Treatment of Susceptible and Multidrug Resistant Community-Acquired Respiratory Tract Infections, published in 2009-12-10, which mentions a compound: 77903-28-7, mainly applied to antibacterial azetidinyl ketolide preparation structure activity respiratory tract infection; crystal structure antibacterial azetidinyl ketolide preparation structure activity, Electric Literature of C7H10N2O.

Respiratory tract bacterial strains are becoming increasingly resistant to currently marketed macrolide antibiotics. The current alternative telithromycin (1) from the newer ketolide class of macrolides addresses resistance but is hampered by serious safety concerns, hepatotoxicity in particular. We have discovered a novel series of azetidinyl ketolides that focus on mitigation of hepatotoxicity by minimizing hepatic turnover and time-dependent inactivation of CYP3A isoforms in the liver without compromising the potency and efficacy of 1.

There is still a lot of research devoted to this compound(SMILES:COC1=C(C)C(N)=CN=C1)Electric Literature of C7H10N2O, and with the development of science, more effects of this compound(77903-28-7) can be discovered.

Reference:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts