Analyzing the synthesis route of 2-(m-Tolyl)ethanol

The synthetic route of 1875-89-4 has been constantly updated, and we look forward to future research findings.

In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 1875-89-4, name is 2-(m-Tolyl)ethanol, the common compound, a new synthetic route is introduced below. name: 2-(m-Tolyl)ethanol

Part A. Preparation of 3-methylphenethyl bromide. To a solution of 3-methylphenethyl alcohol (5.0 g, 36.7 mmol) in methylene chloride at 0° C. was added triphenylphosphine (10.6 g, 40.4 mmol) and carbon tetrabromide (13.4 g, 40.4 mmol). The mixture was allowed to stir with warming to 25° C. for 16 h. The solvent was removed in vacuo and the residue was taken up in ether and filtered through a pad of silica gel. The solvent was removed in vacuo to afford 7.0 g (95percent) of the title bromide.

The synthetic route of 1875-89-4 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; DuPont Pharmaceuticals Company; US6060462; (2000); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts