Extracurricular laboratory: Synthetic route of 1,1-Diphenylethanol

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Each compound has different characteristics, and only by selecting the characteristics of the compound suitable for a specific situation can the compound be applied on a large scale. 599-67-7, name is 1,1-Diphenylethanol. This compound has unique chemical properties. The synthetic route is as follows. name: 1,1-Diphenylethanol

General procedure: In a vacuum dried 100 mL Schlenk flask, benzyl alcohol I (10.0 mmol) and triethylamine(20.0 mmol) were dissolved in THF (50 mL) under Ar atmosphere. Then, HClSiMe2 (12 mmol)was added at room temperature and the resulting mixture was stirred overnight. After the reactionwas complete, the solvent was removed via rotary evaporation. Then, petroleum ether (40 mL)was added. Simple filteration to remove Et3N?HCl and concentration in vacuo could give the pure(hydrido)silyl ether product as a colorless liquid.

If you are interested in these compounds, you can also browse my other articles.Thank you for taking the time to read this article. I hope you enjoyed it, 599-67-7, 1,1-Diphenylethanol.

Reference:
Article; Fang, Huaquan; He, Qiaoxing; Liu, Guixia; Huang, Zheng; Synlett; vol. 28; 18; (2017); p. 2468 – 2472;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts