Electric Literature of 4415-73-0, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 4415-73-0, name is 1,1-Cyclobutanedimethanol. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of [1-(hydroxymethyl)-cyclobutyl]methanol (2.50 g, 21.5 mmol, 1.0 equiv.) which was prepared as described in the reference (F. X. Tavares et al., J. Med. Chem. 2004, 47, 5057-5068) in CH2Cl2 (43 mL) was added SOCl2 (2.35 mL, 32.3 mmol, 1.5 equiv.) slowly at 0 C. After being stirred for 2 h at 25 C., the reaction was diluted (10% MeOH/CH2Cl2) and washed (1×H2O and 1×brine). The organic layer was dried (Na2SO4) and concentrated under reduced pressure to provide the product as a colorless liquid
According to the analysis of related databases, 4415-73-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; Amgen Inc.; US2007/299111; (2007); A1;,
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