The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 111-32-0, name is 4-Methoxybutan-1-ol. This compound has unique chemical properties. The synthetic route is as follows. HPLC of Formula: C5H12O2
Preparation 1-a; 4-Methoxy-butyraldehvde; To an orange suspension of PCC (60 g) in CH2CI2 (700 mL) was added 4- methoxybutan-1-ol (17 g) slowly at 250C. The resulting brown suspension was stirred at 250C for 3.5 h. The reaction mixture was diluted with 1.5 L Et2O and violently stirred at 250C for 10 min. The resulting grey suspension was filtered through celite. The reaction container was washed with 2 x 200 mL Et2O. The organic solutions were combined and passed through celite again. The filtrate was concentrated and the residue was columned on silica gel using 1 :1 hexane/EtOAc to afford 11.0 g of the desired product in 66% yield as colorless oil.
With the rapid development of chemical substances, we look forward to future research findings about 111-32-0.
Reference:
Patent; PFIZER INC.; WO2009/7814; (2009); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts