Related Products of 67853-03-6, In the chemical reaction process,reaction time,type of solvent,can easily affect the result of the reaction, thereby determining the yield and properties of the reaction product.An updated downstream synthesis route of 67853-03-6 as follows.
To a solution of methyl 3-(hydroxymethyl)benzoate (3.0 g) obtained in the above-mentioned reaction and dihydropyran in acetonitrile was added p-toluenesulfonic acid monohydrate, and the mixture was stirred at room temperature for 1 day. Saturated aqueous sodium hydrogen carbonate solution was added, and acetonitrile was evaporated under reduced pressure. The mixture was extracted with ethyl acetate, and the organic layer was washed with saturated aqueous sodium hydrogen carbonate solution and saturated brine. The organic layer was dried over magnesium sulfate, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column (5% ethyl acetate/hexane to 20% ethyl acetate/hexane) to give a brown oil (5.0 g). The object product was used for the next reaction without further purification.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,67853-03-6, its application will become more common.
Reference:
Patent; Taniguchi, Takahiko; Miyata, Kenichi; Kubo, Osamu; Matsui, Junji; US2009/325956; (2009); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts