As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 1883-32-5, name is 2,2-Diphenylethanol, molecular formula is C14H14O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Application In Synthesis of 2,2-Diphenylethanol
General procedure: Substrates, 1 and 2, were synthesized by the same method of 2-adamantyl chloroformate. The triphosgene treated in toluene at 0-4 C (ice bath) for 20 min. The mixture of 2-phenylethanol or 2,2-diphenylethanol with pyridine was prepared in toluene at room temperature. Then the latter mixture was added to the former solution slowly. After the stirring for 1 h, the organic mixture was washed with water and dried by magnesium sulfate. The solvent was removed by the evaporation, the colorless oil (1) or white solid (2) was obtained as a crude product. The substrate 1 was purified from vacuum distillation (120 C and 18 torr) and the substrate 2 was recrystallized by using ligroin. Solvents were purified as described previously.
With the rapid development of chemical substances, we look forward to future research findings about 1883-32-5.
Reference:
Article; Park, Kyoung-Ho; Yang, Gi-Hoon; Kyong, Jin Burm; Bulletin of the Korean Chemical Society; vol. 35; 8; (2014); p. 2263 – 2270;,
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