Application of 75853-18-8, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 75853-18-8, name is 2,3-Difluorobenzyl alcohol. This compound has unique chemical properties. The synthetic route is as follows.
To a solution of (2,3-difluoro-phenyl)-methanol (50 g, 0.35 mol, 1.0 eq) and imidazole (70.9 g, 1.05 mol, 3.0 eq) in dry THF (1 L) was added TBDMSCI (62.7 g, 0.42 mol, 1.2 eq) at ice-bath. After stirring at rt for 3 h, the mixture was extracted with EA, and washed with water and 0.5 N HC1. The organic layer was dried over Na2S04 and evaporated to give the crude product was directly used in next step.
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 75853-18-8, 2,3-Difluorobenzyl alcohol.
Reference:
Patent; LIFESCI PHARMACEUTICALS, INC.; MCDONALD, Andrew; WO2015/103317; (2015); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts