Application of 55362-80-6, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 55362-80-6, name is 9-Bromononan-1-ol, molecular formula is C9H19BrO, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a solution of 9-Bromo- l-nonanol (1.50 g, 6.72 mmol) in acetone (27 ml) cooled at 0C, a satured solution of NaHCO3 (9 ml), NaBr (0.14 g, 1.34 mmol) and 2,2,6,6-Tetramethyl-l-piperidinyloxy-free radical (TEMPO) (0.10 g, 0.67 mmol) were added. Then Trichloroisocyanuric acid (3.1 g, 13.44 mmol) was added portionwise. The mixture was stirred 30 minutes at 0C and 3 hours at room temperature then was cooled at 0C and 2-Propanol (8 ml) was added slowly. The mixture was stirred at 0C for further 30 minutes then the white precipitate was filtered off and the mixture concentrated under reduced pressure. H20 (10 ml) and CH2C12 (10 ml) were added to the residue. The two phases were separated and the aqueous layer was extracted with CH2C12 (2 x 10 ml). The combined organic layers were dried on Na2SO4 and concentrated affording 1.60 g (Yield: 100%) of the title compound as a white solid. 1H NMR (300 MHz, DMSO) delta 3.49 (t, 2H), 2.23 – 2.08 (m, 2H), 1.84 – 1.68 (m, 2H), 1.57 – 1.14 (m, 10H).
While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 55362-80-6, 9-Bromononan-1-ol.
Reference:
Patent; NICOX S.A.; RONSIN, Gael; STORONI, Laura; BENEDINI, Francesca; WO2013/60673; (2013); A1;,
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