Adding a certain compound to certain chemical reactions, such as: 3562-73-0, 1-(4-Biphenylyl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, name: 1-(4-Biphenylyl)ethanol, blongs to alcohols-buliding-blocks compound. name: 1-(4-Biphenylyl)ethanol
h): Take a reaction tube and add sodium azide 49mg.1-[4-(1,1′-biphenyl)]ethanol 59.5 mg,400 uL of trifluoroacetic acid, 150 uL of methanesulfonic acid, 1.0 mL of n-hexane, and stirred at 50 C for 36 hours.After the reaction was completed, 10 mL of a sodium hydroxide solution was added to quench the reaction, and the mixture was extracted with ethyl acetate three times.The organic phase was washed with 5 mL of brine, and the organic phases were combined and separated by column chromatography to obtain 45.7 mg of p-phenylaniline.The yield was 90%.
At the same time, in my other blogs, there are other synthetic methods of this type of compound,3562-73-0, 1-(4-Biphenylyl)ethanol, and friends who are interested can also refer to it.
Reference:
Patent; Peking University; Jiao Ning; Liu Jianzhong; (27 pag.)CN109134267; (2019); A;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts