Adding a certain compound to certain chemical reactions, such as: 13726-17-5, (4-Chloro-3-methoxyphenyl)methanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Computed Properties of C8H9ClO2, blongs to alcohols-buliding-blocks compound. Computed Properties of C8H9ClO2
D. Synthesis of 4-chloro-3-methoxybenzaldehyde (0202) To a solution of (4-chloro-3-methoxyphenyl)methan-1-ol (5.08 g, 29.4 mmol) in benzene (120 mL) was added MnO2 (5.65 g, 65 mmol). The reaction mixture was refluxed for 17 hr, chilled, and filtered through Celite, washing the cake with CH2Cl2 (300mL). The filtrate was concentrated in vacuo to give 4-chloro-3-methoxybenzaldehyde (4.5 g, 89%).
At the same time, in my other blogs, there are other synthetic methods of this type of compound,13726-17-5, (4-Chloro-3-methoxyphenyl)methanol, and friends who are interested can also refer to it.
Reference:
Patent; Portola Pharmaceuticals, Inc.; Scarborough, Robert; Jantzen, Hans-Michael; Huang, Wolin; Sedlock, David; Marlowe, Charles; Kane-Maguire, Kim; (200 pag.)EP2314593; (2016); B1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts