Adding a certain compound to certain chemical reactions, such as: 15484-46-5, Methyl 2-(hydroxymethyl)acrylate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 15484-46-5, blongs to alcohols-buliding-blocks compound. Recommanded Product: 15484-46-5
Trifluoromethanesulfonic anhydride (25.0 g) and dichloromethane (80.0 ml) were put into a reaction vessel and cooled to 0 C. Compound (T-8) (10.3 g) and a dichloromethane (160 ml) solution containing trimethylamine (8.97 g) were slowly added dropwise thereto. The obtained solution was poured into 1,6-hexanediol (314 g) and the mixture was stirred at room temperature for 12 hours. The reaction mixture was poured into water, and an aqueous layer was extracted with dichloromethane. The obtained organic layer was washed with water and dried with anhydrous magnesium sulfate. This solution was concentrated under a reduced pressure, and the residue was purified through silica gel chromatography (volume ratio, heptane:ethyl acetate=3:2), and thereby Compound (T-9) (11.3 g; 59%) was obtained.
The synthetic route of 15484-46-5 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; JNC CORPORATION; JNC PETROCHEMICAL CORPORATION; TANAKA, Hiroyuki; (95 pag.)US2019/390115; (2019); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts