Related Products of 111-32-0, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 111-32-0, name is 4-Methoxybutan-1-ol, molecular formula is C5H12O2, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
4-MethoxybutanalTo a solution of 4-methoxybutan-1-ol (3 g, 28.8 mmol) in DCM (30 mL) was added PCC (9.31 g, 43.2 mmol) at 0 C.The reaction was stirred at RT for 1 h. The reaction mixture was filtered through celite, and washed with DCM (2X). The filtrate was concentrated to afford 4-methoxybutanal (1.5 g, 14.69 mmol, 51.0 % yield). H NMR (400 MHz, DMSO-d6) delta ppm 9.65 (s, 1 H), 4.00 (m, 2H), 3.30 (bs, 3H), 2.5 (m, 2H), 1.6 (m, 2H)
According to the analysis of related databases, 111-32-0, the application of this compound in the production field has become more and more popular.
Reference:
Patent; GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED; ASTEX THERAPEUTICS LIMITED; BOEHM, Jeffrey Charles; DAVIES, Thomas Glanmor; WOOLFORD, Alison Jo-anne; GRIFFITHS-JONES, Charlotte Mary; WILLEMS, Hendrika Maria Gerarda; NORTON, David; SAXTY, Gordon; HEIGHTMAN, Thomas Daniel; LI, Tindy; KERNS, Jeffrey K.; DAVIS, Roderick S.; YAN, Hongxing; WO2015/92713; (2015); A1;,
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