The origin of a common compound about 87327-65-9

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 87327-65-9, 1-(2,6-Difluorophenyl)ethanol.

Application of 87327-65-9, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 87327-65-9, name is 1-(2,6-Difluorophenyl)ethanol. This compound has unique chemical properties. The synthetic route is as follows.

Example 82; 5- [1-(2,6- Difluorophenyl)-ethoxy ]-q uinazoline-2,4-diamine; [00258] Step 1; To a cold (ice water) suspension of sodium hydride (409 mg; 10 mmol) in anhydrous DMF (4 mL) is added a solution of 2,6-difluoro-alpha- methylbenzyl alcohol (1.63 g; 10 mmol) in anhydrous DMF (5 mL) over 10 minutes. After allowing to room temperature over 1 hour, this solution is added to a cold (ice water) stirred solution of 2,6-difluorobenzonitrile (1.53 g; 11 mmol) in anhydrous DMF (6 mL), and allowed to room temperature over 2.5 hours. The reaction mixture is poured into ice water with vigorous stirring and the resulting solid is filtered, washed with water, and dried under vacuum at 40 C overnight to give 1.92 grams of 2-[ 1-(2,6-difluorophenyl)-ethoxy]-6-fluorobenzonitrile.

While traditionally a conservative industry, chemical producers will need to modernize their PR strategies to stay relevant.we look forward to future research findings about 87327-65-9, 1-(2,6-Difluorophenyl)ethanol.

Reference:
Patent; DECODE CHEMISTRY, INC.; SINGH, Jasbir; GURNEY, Mark E.; WO2005/123724; (2005); A1;,
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