New downstream synthetic route of 2-Amino-2-(4-fluorophenyl)ethanol

The synthetic route of 140373-17-7 has been constantly updated, and we look forward to future research findings.

Application of 140373-17-7 , The common heterocyclic compound, 140373-17-7, name is 2-Amino-2-(4-fluorophenyl)ethanol, molecular formula is C8H10FNO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.

Method E, Step 5Compound E5 will be reacted with E6 and EDCI in DMF to give compound E7 after purification.

The synthetic route of 140373-17-7 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; SCHERING CORPORATION; WO2009/61699; (2009); A1;,
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts