Related Products of 230295-16-6, The major producers of chemicals have been the Europe, Japan and China. Due to the growing call for a cleaner, greener environment, people will have to find innovative ways to maintain their relevance. Here is a compound 230295-16-6, name is (3-Fluoro-4-(trifluoromethyl)phenyl)methanol. This compound has unique chemical properties. The synthetic route is as follows.
Step2: A mixture of [3-fluoro-4-(trifluoromethyl)phenyl]methanol (230 g, 1.18 mol) andHBr (1200 mL, 40%) was heated to reflux for 2 hours. The resulting solution was cooledand diluted with 2 L of water. The resulting solution was extracted with dichloromethane (3 x 1 L). The organic layers were combined, washed with water (1 L), aqueous sodium bicarbonate (1 L) and brine (1 L), dried over anhydrous sodium sulfate and concentrated under vacuum. This resulted in 4-(bromomethyl)-2-fluoro-1-(trifluoromethyl)benzene asyellow oil.
According to the analysis of related databases, 230295-16-6, the application of this compound in the production field has become more and more popular.
Reference:
Patent; MERCK SHARP & DOHME CORP.; CAMMARANO, Carolyn Michele; CHRISTOPHER, Matthew, P.; DINSMORE, Christopher; DOLL, Ronald, J.; FRADERA LLINAS, Francesc Xavier; LI, Chaomin; MACHACEK, Michelle; MARTINEZ, Michelle; NAIR, Latha, G.; PAN, Weidong; REUTERSHAN, Michael Hale; SHIZUKA, Manami; STEINHUEBEL, Dietrich, P.; SUN, Binyuan; THOMPSON, Christopher Francis; TROTTER, B. Wesley; VOSS, Matthew Ernst; WANG, Yaolin; YANG, Liping; PANDA, Jagannath; KURISSERY, Anthappan Tony; BOGEN, Stephane, L.; WO2014/120748; (2014); A1;,
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