Application of 2009-83-8, Adding some certain compound to certain chemical reactions, such as: 2009-83-8, name is 6-Chlorohexan-1-ol,molecular formula is C6H13ClO, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound 2009-83-8.
To a 50 mL glass three-neck flask was added 2.72 g (0.01 mol) of 8-hydroxy-1,1,7,7-tetramethyljulonidine-9- Formaldehyde, 2.05 g (0.015 mol) 6-chloro-1-hexanol and 30 mL re-distilled N,N-dimethylformamide, add dry anhydrous potassium carbonate 1.7 g (0.012 mol) under N2 protection, at 120C The reaction was continued overnight . After the reaction was complete, the temperature was lowered. Potassium carbonate was removed by filtration. The filtrate was poured into water to obtain a dark blue solution, which was extracted three times with ethyl acetate. The organic phases were combined and the combined organic phases were dried over anhydrous magnesium sulfate and left overnight. , Filtration, rotary evaporation to remove ethyl acetate, the residue was separated by column chromatography (200-300 mesh silica gel as the stationary phase, with a mixture of n-hexane and ethyl acetate as the mobile phase, where: n-hexane and ethyl acetate The volume ratio was 7:1). After drying, a yellow solid was obtained as compound 1 in a yield of 61%.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 2009-83-8, 6-Chlorohexan-1-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Chinese Academy Of Sciences Physics And Chemistry Technology Institute; Zhen Zhen; Zhang Airui; Bo Shuhui; Liu Xinhou; Qiu Ling; Zhang Maolin; Xu Huajun; (21 pag.)CN104558005; (2018); B;,
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