Adding a certain compound to certain chemical reactions, such as: 140373-17-7, 2-Amino-2-(4-fluorophenyl)ethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 140373-17-7, blongs to alcohols-buliding-blocks compound. name: 2-Amino-2-(4-fluorophenyl)ethanol
step 1 4- (4-fluorophenyl) oxazolidin-2-one2-amino-2- (4-fluorophenyl) ethan-1-ol 600mg and diethyl carbonate 914mg potassium carbonate 80mg It was suspended in, and stirred for 2.5 hours at 130 , further stirred for 2.5 hours at 100 , except for the ethanol to produce.The reaction mixture was diluted with ethyl acetate, washed successively with water and saturated brine, and dried with magnesium sulfate.Under reduced pressure, the solvent was distilled off, to give the title compound 610mg as a pale yellow oil.
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,140373-17-7, its application will become more common.
Reference:
Patent; NIPPON SHINYAKU COMPANY LIMITED; FUJIHARA, HIDETAKA; ASAKI, TETSUO; HORI, KATSUTOSHI; NAITO, HARUNA; (146 pag.)JP5668756; (2015); B2;,
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