In the next few decades, the world population will flourish. As the population grows rapidly and people all over the world use more and more resources, all industries must consider their environmental impact. 2807-30-9, name is 2-Propoxyethanol, the common compound, a new synthetic route is introduced below. name: 2-Propoxyethanol
Compound 2 (100 mg,0.15 mmol) was treated with 30% HBr/acetic acid (5 ml), and theresulted solution was stirred at room temperature for 2 h. Severaltypes of alcohol (50 ml) were added to the solution, and themixture was stirred at 30e80 C for 4 h under N2 protection. Then50 mL of DCM was added and separated, the combined organiclayers were washed with water (3 50 mL). The solvent wasevaporated and the residue was dissolved in THF (5 mL). Theresulted solution was treated with 1M LiOH (0.75 mL, 0.75 mmol),and the resulting mixture was stirred at room temperature for1e2 h. 1 M HCl solution was added to the mixture until pH 3 wasattained. Then the suspensionwas extracted with DCM (3 50 mL).The combined organic layers were washed with water (3 50 mL)and dried over anhydrous Na2SO4. The organic solvent wasremoved under reduced pressure and the residue was purified bycolumn chromatography over silica gel to afford black solid 5e13.
The synthetic route of 2807-30-9 has been constantly updated, and we look forward to future research findings.
Reference:
Article; Chen, Dan-Ye; Chen, Zhi-Long; Gao, Ying-Hua; O’Shea, Donal F.; Wu, Dan; Wu, Xiao-Feng; Yan, Yi-Jia; Zhu, Wei; Zhu, Xue-Xue; European Journal of Medicinal Chemistry; vol. 187; (2020);,
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