Adding a certain compound to certain chemical reactions, such as: 5299-60-5, Ethyl 6-hydroxyhexanoate, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 5299-60-5, blongs to alcohols-buliding-blocks compound. Computed Properties of C8H16O3
PREPARATION 280 To a solution of pyridinium chlorochromate (2.0 g) in dichloromethane (15 ml) was added a solution of 6-hydroxyhexanoic acid ethyl ester (1.0 g) in dichloromethane (1.5 ml) in one portion and stirred for 1.5 hours at ambient temperature. Ether (15 ml) was added to the reaction mixture, and the insoluble material removed by filtration and discarded. The filtrate was purified by silica gel chromatography (diethyl ether) to give 6-oxohexanoic acid ethyl ester (884.6 mg), as a pale green oil. IR (KBr): 2981.4, 2940.9, 2871.5, 2827.1, 2723.0, 1731.8, 1184.1 cm-1. NMR (CDCl3, delta): 1.26 (3H, t, J=7.1 Hz), 1.5-1.8 (4H, m), 2.2-2.6 (4H, m), 4.13 (2H, q, J=7.1 Hz), 9.77 (1H, t, J=1.6 Hz).
These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,5299-60-5, its application will become more common.
Reference:
Patent; Fujisawa Pharmaceutical Co., Ltd.; US6884868; (2005); B1;,
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