A new synthetic route of 1,1-Diphenylethanol

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,599-67-7, its application will become more common.

Adding a certain compound to certain chemical reactions, such as: 599-67-7, 1,1-Diphenylethanol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, 599-67-7, blongs to alcohols-buliding-blocks compound. Computed Properties of C14H14O

General procedure: A solvent (5 mL) was placed in a 10 mL round bottom-flask equipped with a magnetic stirrerunder reflux, NXS (1.1 mmol) was then added and, after being dissolved, the substrate (1 mmol) wasadded and the solution was stirred for 4-24 h. The progress of the reaction mixture was monitoredby TLC, whilst the consumption of NXS was tested by KI (0.1 M). Upon completion of the reaction,the crude reaction mixture was cooled down at room temperature, diluted with EtOAc (15 mL),washed with aqueous Na2S2O3 (6 mL), NaHCO3 (6 mL), and water (10 mL), and dried over anhydrousNa2SO4. The solvent was evaporated under reduced pressure and the crude product obtained wasanalyzed by 1H-NMR. The pure final products were obtained after flash chromatography, columnchromatography or preparative thin layer chromatography.

These compound has a wide range of applications. It is believed that with the continuous development of the source of the synthetic route,599-67-7, its application will become more common.

Reference:
Article; Ajvazi, Njomza; Stavber, Stojan; Molecules; vol. 21; 10; (2016);,
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