Let¡¯s face it, organic chemistry can seem difficult to learn. Especially from a beginner¡¯s point of view. Like 870-72-4, Name is Hydroxymethanesulfonic Acid Sodium Salt. In a document, author is Shirani, Maryam, introducing its new discovery. Formula: CH3NaO4S.
An ultra-sensitive optical aptasensor based on gold nanoparticles/poly vinyl alcohol hydrogel as acceptor/emitter pair for fluorometric detection of digoxin with on/off/on strategy
A novel nanobiosensor was prepared by aptamer and gold nanoparticles conjugate in poly vinyl alcohol hydrogel for sensitive detection of digoxin in human plasma samples. The developed nanobiosensor was characterized by Fourier transform infrared spectroscopy, transmission electron microscopy, and dynamic light scattering instrument. In this sensor the hydrogel acted as a fluorescent probe. The fluorescence intensity of the hydrogel was quenched by aptamer stabilized gold nanoparticles as energy acceptor. Upon addition of digoxin, the aptamer/drug complex was formed and the fluorescence of the hydrogel was restored because of destabilization and aggregation of gold nanoparticles in the presence of salt. The affecting parameters on the nanobiosensor performance were assessed and under the optimized conditions the external and in plasma calibration curves were linear in the 10-1000 ng L-1 digoxin concentration range with detection limits of 2.9 and 3.1 ng L-1, respectively. The relative standard devi-ations for 5 replicate determinations of 50, 250, and 500 ng L-1 of digoxin, were 7.3, 5.1, and 3.8%, respec-tively. This nanofluoroprobe was successfully applied for determination of digoxin in spiked plasma samples without any pretreatment procedure. (C) 2020 Elsevier B.V. All rights reserved.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 870-72-4 help many people in the next few years. Formula: CH3NaO4S.
Reference:
Alcohol – Wikipedia,
,Alcohols – Chemistry LibreTexts