As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 769-30-2, name is Benzo[d][1,3]dioxol-4-ylmethanol, molecular formula is C8H8O3, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below. Formula: C8H8O3
Benzo[d][1,3]dioxo-4-ylmethanol (223 mg, 1.47 mmol)Dissolved in dichloromethane (10 mL), then phosphorus tribromide (0.17 mL, 1.8 mmol) was added dropwise at 0 C.After the completion of the dropwise addition, the mixture was stirred at room temperature for 3 hours.The reaction was quenched with saturated aqueous sodium bicarbonate and extracted with dichloromethane (50
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