Adding a certain compound to certain chemical reactions, such as: 13401-56-4, 3-Chloro-2,2-dimethylpropan-1-ol, can increase the reaction rate and produce products with better performance than those obtained under traditional synthetic methods. Here is a downstream synthesis route of the compound, Recommanded Product: 3-Chloro-2,2-dimethylpropan-1-ol, blongs to alcohols-buliding-blocks compound. Recommanded Product: 3-Chloro-2,2-dimethylpropan-1-ol
Reference Production Example 6; In 5 ml of tetrahydrofuran was suspended 0.14 g of sodium hydride (60% in oil), to which 0.5 ml of a solution containing 0.36 g of 3-chloro-2,2- dimethyl-1-propanol was added dropwise at 0C, followed by stirring for 10 minutes. To this was added dropwise 0.5 ml of tetrahydrofuran containing 0.4 g of 4,6-dichloropyrimidine dissolved therein, followed by stirring at the same temperature for 2 hours. The reaction mixture was then poured into a saturated aqueous ammonium chloride solution, which was extracted three times with t-butyl methyl ether. The combined organic layers were washed with a saturated aqueous sodium chloride solution, dried over anhydrous magnesium sulfate, and then concentrated. The residue was subjected to silica gel column chromatography to give 0.62 g of 4-chloro-6- (3-chloro-2, 2- dimethylpropyloxy) pyrimidine. 4-Chloro-6- (3-chloro-2, 2-dimethylpropyloxy) pyrimidine ‘H-NMR : 1. 11 (s, 6H), 3.51 (s, 2H), 4.23 (s, 2H), 6.81 (s, 1H), 8.57 (s, 1H).
The synthetic route of 13401-56-4 has been constantly updated, and we look forward to future research findings.
Reference:
Patent; SUMITOMO CHEMICAL COMPANY, LIMITED; WO2003/76415; (2003); A1;,
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