617-94-7, As we all know, there are many different methods for the synthesis of a compound, and people can choose the synthesis method that suits their own laboratory according to the actual situation. 617-94-7, name is 2-Phenyl-2-propanol, molecular formula is C9H12O, The compound is widely used in many fields, so it is necessary to find a new synthetic route. The downstream synthesis method of this compound is introduced below.
To a solution of NaH (60 % dispersion in mineral oil, 105 mg, 9.61 mmol) in diethylether (9.5 ml)was added alpha,alpha-dimethyl benzenemethanol (3.04 g, 22.3 mmol) at 0 C. After stirring for 40 min atr oom temperature, trichloroacetonitrile (2.0 ml, 20.0 mmol) was added at 0 C. The reaction mixture was stirred for 3 h at room temperature and concentrated in vacuo. Hexane (2.5 ml) and MeOH (0.1ml) were added to the resulting residue. The mixture was filtered through Celite and concentrated invacuo to give S11 (4.85 g, 78%).
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 617-94-7, 2-Phenyl-2-propanol, other downstream synthetic routes, hurry up and to see.
Reference:
Article; Ota, Eisuke; Mikame, Yu; Hirai, Go; Nishiyama, Shigeru; Sodeoka, Mikiko; Synlett; vol. 27; 7; (2016); p. 1128 – 1132;,
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