Related Products of 6282-88-8 ,Some common heterocyclic compound, 6282-88-8, molecular formula is C9H11ClO, its traditional synthetic route has been very mature, but the traditional synthetic route has various shortcomings, such as complicated route, low yield, poor purity, etc., below Introduce a new synthetic route.
(f) 135 ml of pyridine are added dropwise to 150 g of 3-(4-chlorophenyl)-propan-1-ol and 206.6 g of p-toluenesulphonyl chloride in 300 ml of chloroform at 0. After the addition, the mixture is stirred at room temperature for 3 hours and the solution is poured into a mixture of 400 ml of water and 120 ml of concentrated hydrochloric acid. The organic phase is separated off, washed 3 times with water, dried over sodium sulphate and concentrated to a yellowish viscous oil in vacuo, yield: 285 g of p-toluenesulphonic acid 3-(4-chlorophenyl)-propyl ester.
In the field of chemistry, the synthetic routes of compounds are constantly being developed and updated. I will also mention this compound in other articles. 6282-88-8, 3-(4-Chlorophenyl)propan-1-ol, other downstream synthetic routes, hurry up and to see.
Reference:
Patent; Byk Gulden Lomberg Chemische Fabrik Gesellschaft; US4334089; (1982); A;,
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