Cytostatic activity of some novel amidocarbamate derivatives of ketoprofen was written by Sahoo, Prasanta Kumar;Behera, Pritishova. And the article was included in Journal of Cancer Therapy in 2010.HPLC of Formula: 59960-32-6 This article mentions the following:
A series of novel ketoprofen derivatives bearing both amide and carbamate functionalities were prepared using benzotriazole. Selective reduction of ketoprofen produced 3-(HOCHPh)C6H4CHMeCO2H, which reacts with one or two moles of 1-benzotriazolecarboxylic acid chloride to give the mono- and bis(benzotriazole) derivatives, the latter being aminated to give the title products. Antioxidative screenings revealed that the prepared compounds possess excellent lipid peroxidation inhibition at 0.1 mM concentration 3-(RCO2CHPh)C6H4CHMeCOR [R = 1-benzotriazolyl, NHCH2Ph] also showed high soybean lipoxygenase inhibition activity, whereas the amidocarbamate derivatives of ketoprofen showed only weak reducing activity against 1,1-diphenyl-2-picrylhydrazyl radicals. No selective effects were noted for the tested compounds against a broad variety of DNA and RNA viruses. The majority of the compounds show IC50 values around 10-25 μM, pointing to a relatively minor role of the R substituents on the core structure for cytostatic activity, as long as a bulky lipophilic (cyclic) entity is present. Also, the presence of the amide groups might play an important role to eventually exert cytostatic potential. In the experiment, the researchers used many compounds, for example, 2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6HPLC of Formula: 59960-32-6).
2-(3-(Hydroxy(phenyl)methyl)phenyl)propanoic acid (cas: 59960-32-6) belongs to alcohols. Because alcohols are easily synthesized and easily transformed into other compounds, they serve as important intermediates in organic synthesis. Grignard and organolithium reagents are powerful tools for organic synthesis, and the most common products of their reactions are alcohols.HPLC of Formula: 59960-32-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts