Heteroaryl-O-glucosides as novel sodium glucose co-transporter 2 inhibitors. Part 1 was written by Zhang, Xiaoyan;Urbanski, Maud;Patel, Mona;Zeck, Roxanne E.;Cox, Geoffrey G.;Bian, Haiyan;Conway, Bruce R.;Beavers, Mary Pat;Rybczynski, Philip J.;Demarest, Keith T.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2005.Application of 1634-34-0 This article mentions the following:
A series of benzo-fused heteroaryl-O-glucosides was synthesized and evaluated in SGLT1 and SGLT2 cell-based functional assays. Indole-O-glucoside and benzimidazole-O-glucoside exhibited potent in vitro SGLT2 inhibitory activity. In the experiment, the researchers used many compounds, for example, 2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0Application of 1634-34-0).
2′,6′-Dihydroxy-4′-methylacetophenone (cas: 1634-34-0) belongs to alcohols. Alcohols are among the most common organic compounds. They are used as sweeteners and in making perfumes, are valuable intermediates in the synthesis of other compounds, and are among the most abundantly produced organic chemicals in industry. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 1634-34-0
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts