Discovery of practical production processes for arylsulfur pentafluorides and their higher homologs, bis- and tris-(sulfur pentafluorides): beginning of a new era of super-trifluoromethyl arene chemistry and its industry was written by Umemoto, Teruo;Garrick, Lloyd M.;Saito, Norimichi. And the article was included in Beilstein Journal of Organic Chemistry in 2012.Application of 29364-29-2 This article mentions the following:
Various arylsulfur pentafluorides, ArSF5, have long been desired in both academic and industrial areas and ArSF5 compounds have attracted considerable interest in many areas such as medicine, agrochems., and other new materials, since the highly stable SF5 group is considered a super-trifluoromethyl group due to its significantly higher electronegativity and lipophilicity. This article describes the first practical method for the production of various arylsulfur pentafluorides and their higher homologs, bis- and tris-(sulfur pentafluorides), from the corresponding diaryl disulfides or aryl thiols. The method consists of two steps: (step 1) treatment of a diaryl disulfide or an aryl thiol with chlorine in the presence of an alkali metal fluoride and (step 2) treatment of the resulting arylsulfur chlorotetrafluoride with a fluoride source, such as zinc fluoride (ZnF2), hydrofluoric acid (HF) and antimony fluorides, Sb(III/V) fluorides. The intermediate arylsulfur chlorotetrafluoride derivatives were isolated by distillation or recrystallization and characterized. The aspects of these new reactions are revealed and reaction mechanisms are discussed. As the method offers considerable improvement over previous methods in cost, yield, practicality, applicability and large-scale production, the new processes described here can be employed as the first practical method for the economical production of various arylsulfur pentafluorides and their higher homologs, which could then open up a new era of super-trifluoromethyl arene chem. and its applications in many areas. A reaction (chlorine/potassium fluoride) of bis(2,3,6-trifluorophenyl)disulfide (I) gave trans-chlorotetrafluoro(2,3,6-trifluorophenyl)sulfur (II) and cis-chlorotetrafluoro(2,3,6-trifluorophenyl)sulfur (III). The synthesis of the target compound was achieve by the treatment of II, III with fluorination agents, to provide, e.g., pentafluoro(2,3,6-trifluorophenyl)sulfur (IV). In the experiment, the researchers used many compounds, for example, Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2Application of 29364-29-2).
Sodium 2-methyl-2-propanethiolate (cas: 29364-29-2) belongs to alcohols. Alcohols are weak acids. The most acidic simple alcohols (methanol and ethanol) are about as acidic as water, and most other alcohols are somewhat less acidic. Under carefully controlled conditions, simple alcohols can undergo intermolecular dehydration to give ethers. This reaction is effective only with methanol, ethanol, and other simple primary alcohols.Application of 29364-29-2
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts