Transformation of Alkynes into Chiral Alcohols via TfOH-Catalyzed Hydration and Ru-Catalyzed Tandem Asymmetric Hydrogenation was written by Liu, Sensheng;Liu, Huan;Zhou, Haifeng;Liu, Qixing;Lv, Jinliang. And the article was included in Organic Letters in 2018.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol This article mentions the following:
A novel full atom-economic process for the transformation of alkynes into chiral alcs. by TfOH-catalyzed hydration coupled with Ru-catalyzed tandem asym. hydrogenation in TFE under simple conditions has been developed. A range of chiral alcs. was obtained with broad functional group tolerance, good yields, and excellent stereoselectivities. In the experiment, the researchers used many compounds, for example, (S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol).
(S)-1-(2-Fluorophenyl)ethanol (cas: 171032-87-4) belongs to alcohols. Under appropriate conditions, inorganic acids also react with alcohols to form esters. To form these esters, a wide variety of specialized reagents and conditions can be used. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: (S)-1-(2-Fluorophenyl)ethanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts