CuO-Fe(III)-Zeolite-Y as efficient catalyst for oxidative alcohol-amine coupling reactions was written by Gogoi, Gautam;Baruah, Manash J.;Biswas, Subir;Hoque, Nazimul;Lee, Seonghwan;Park, Young-Bin;Saikia, Lakshi;Bania, Kusum K.. And the article was included in Molecular Catalysis in 2022.Application In Synthesis of (2,4-Dichlorophenyl)methanol This article mentions the following:
CuO nanocatalyst with layered structure was supported over Fe-exchanged zeolite-Y (CuO-Fe(III)-Y) for selective synthesis of amides by oxidative coupling of aromatic primary alcs. and amines. The CuO-Fe(III)-Y catalyst was characterized by different physicochem. and spectroscopic techniques. The amide bond formation reaction was found to occur in absence of any external base and reagents. The temperature-programmed desorption (TPD) study predicted the development of strong basic sites in the CuO-Fe(III)-Y catalyst that boosted the dehydrogenative coupling process. The activity of the material in such coupling reaction was found to be comparable to those of other costly metal catalysts under different reaction conditions. The product yield of the reaction was found to be substrate-dependent giving moderate to maximum yield of 85%. The anomalies in the reaction appeared in case of 5-nitro-2-chloro-benzylalc. that undergoes a C-N coupling product through C-Cl bond activation. The mechanism of the reaction was believed to proceed through FeIV=O species that helped in the activation of the benzylic C-H bond . In the experiment, the researchers used many compounds, for example, (2,4-Dichlorophenyl)methanol (cas: 1777-82-8Application In Synthesis of (2,4-Dichlorophenyl)methanol).
(2,4-Dichlorophenyl)methanol (cas: 1777-82-8) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Secondary alcohols are easily oxidized without breaking carbon-carbon bonds only as far as the ketone stage. No further oxidation is seen except under very stringent conditions.Application In Synthesis of (2,4-Dichlorophenyl)methanol
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts