Asymmetric amination of meso-epoxide with vegetable powder as a low-toxicity catalyst was written by Takeuchi, Yuki;Asano, Tatsuhiro;Tsuzaki, Kazuya;Wada, Koichi;Kurata, Hiroyuki. And the article was included in Molecules in 2020.Recommanded Product: 40571-86-6 This article mentions the following:
This paper describes the scope and limitation of substrates subjected to asym. amination with epoxides catalyzed by a soluble soybean polysaccharide (Soyafibe S-DN), which we recently discovered from the reaction of 1,2-epoxycyclohexane with cyclopropylamine. Various meso-epoxides reacted with various amines afforded the corresponding products with good enantiomeric selectivity. Since it was found that pectin was found to have a catalytic ability after screening com. available polysaccharides, we studied 33 different vegetable powders having pectic substances, and we found that many vegetable powders showed catalytic ability. These results should guide in using vegetable components as low-toxic catalysts for the production of pharmaceuticals. In the experiment, the researchers used many compounds, for example, Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6Recommanded Product: 40571-86-6).
Trans-2-(benzylamino)cyclohexanol (cas: 40571-86-6) belongs to alcohols. Alkyl halides are often synthesized from alcohols, in effect substituting a halogen atom for the hydroxyl group. Converting an alcohol to an alkene requires removal of the hydroxyl group and a hydrogen atom on the neighbouring carbon atom. Dehydrations are most commonly carried out by warming the alcohol in the presence of a strong dehydrating acid, such as concentrated sulfuric acid.Recommanded Product: 40571-86-6
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts