Karsai, Syrus’s team published research in Dermatologic Therapy in 34 | CAS: 111-29-5

Dermatologic Therapy published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Product Details of C5H12O2.

Karsai, Syrus published the artcileComparison of novel aluminium lactate versus aluminium chloride-based antiperspirant in excessive axillary perspiration: First prospective cohort study, Product Details of C5H12O2, the publication is Dermatologic Therapy (2021), 34(4), e15020, database is CAplus and MEDLINE.

Aluminum chloride-based antiperspirants are an effective topical therapeutic option for mild to moderate states of excessive perspiration. Its use is primarily limited by the occurrence of skin irritation, especially in sensitive skin types. The objective of this study was to compare the antiperspirant efficacy and tolerability of a novel antiperspirant with 12.5% aluminum lactate, and a 12.5% aluminum chloride-based antiperspirant. This cohort study was conducted as a two-sided self-assessment comparison between both preparations in healthy volunteers to generate selfcare-related data. Almost half of the participants stated that aluminum chloride was more efficacious than aluminum lactate; 22% stated aluminum lactate was more efficacious than aluminum chloride; 28% observed no difference in the efficacy of both preparations (p = 0.04). However, 88% described greater tolerability with aluminum lactate (p < 0.0001). In this study, aluminum lactate showed significantly greater tolerability than aluminum chloride, although the latter tended to show slightly greater efficacy.

Dermatologic Therapy published new progress about 111-29-5. 111-29-5 belongs to alcohols-buliding-blocks, auxiliary class Aliphatic hydrocarbon chain,Alcohol,Ploymers, name is Pentane-1,5-diol, and the molecular formula is C5H12O2, Product Details of C5H12O2.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts