Newell, Grace E. published the artcilePreparation of a clickable monomer compatible with automated PNA synthesis, Category: alcohols-buliding-blocks, the main research area is peptide nucleic acid thymine monomer synthesis; reductive amination PNA monomer incorporation PNA Click chem.
A propargyl-containing Fmoc-protected (Fmoc = 9-fluorenylmethoxycarbonyl) thymine monomer was synthesized for possible use in the pre- or post-functionalization of PNA oligomers via Click chem. The monomer should be suitable for incorporation in normal automated solid phase PNA synthesis. The synthesis is suitable for the preparation of gram-quantities of monomers and uses reductive amination as the key step.
Tetrahedron Letters published new progress about Click chemistry. 22483-09-6 belongs to class alcohols-buliding-blocks, name is 2,2-Dimethoxyethanamine, and the molecular formula is C4H11NO2, Category: alcohols-buliding-blocks.
Referemce:
Alcohol – Wikipedia,
Alcohols – Chemistry LibreTexts