Weinstock, Leonard M. published the artcileSynthesis of the β-adrenergic blocking agent timolol from optically active precursors, SDS of cas: 30165-97-0, the publication is Journal of Organic Chemistry (1976), 41(19), 3121-4, database is CAplus and MEDLINE.
The β-adrenergic blocking agent, trimolol (I), was prepared from R-glyceraldehyde via catalytic hydrogenation over Pd in the presence of Me3CNH2. Treating with PHCHO and then with II in the presence of Me3COK and acid hydrolysis gave 50% I.
Journal of Organic Chemistry published new progress about 30165-97-0. 30165-97-0 belongs to alcohols-buliding-blocks, auxiliary class Morpholine,Thiadiazole,Alcohol, name is 4-Morpholino-1,2,5-thiadiazol-3-ol, and the molecular formula is C9H9NO, SDS of cas: 30165-97-0.
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