Grigg, R.’s team published research in Journal of the Chemical Society, Chemical Communications in | CAS: 4543-95-7

Journal of the Chemical Society, Chemical Communications published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, SDS of cas: 4543-95-7.

Grigg, R. published the artcileTransition metal-catalyzed N-alkylation of amines by alcohols, SDS of cas: 4543-95-7, the publication is Journal of the Chemical Society, Chemical Communications (1981), 611-12, database is CAplus.

Primary and secondary alcs. alkylate primary and secondary alkyl and heterocyclic amines in the presence of Rh, Ir and Ru compounds at ≤100° to give monoalkylated products. Thus, BuNH2 was refluxed 8 h in MeOH with RhH(PPh3)4 (I) to give 98% BuNHMe. Heterocyclic rings were prepared by inter- or intramol. alkylation. E.g., BuN(CH2)4OH was refluxed in dioxane with I to give 56% N-butyltetrahydropyrrole.

Journal of the Chemical Society, Chemical Communications published new progress about 4543-95-7. 4543-95-7 belongs to alcohols-buliding-blocks, auxiliary class Amine,Aliphatic hydrocarbon chain,Alcohol, name is 4-(Butylamino)butan-1-ol, and the molecular formula is C8H19NO, SDS of cas: 4543-95-7.

Referemce:
https://en.wikipedia.org/wiki/Alcohol,
Alcohols – Chemistry LibreTexts